EP.TH.299Is peritoneal lavage with water the optimal washout as a preventative method for peritoneal disease following colorectal cancer resection? A systematic review

Abstract Aim To study available data on the advantages of peritoneal lavage with distilled water following colorectal cancer resection in improving overall patient outcomes Methods PubMed, Google Scholar, and Cochrane databases were searched until October 2020. References from relevant articles reviewed to widen search. Results Overall, 3 experimental studies identified. Water was found be superior other solutions inducing tumorigenic cell lysis vitro. Mice who underwent survived longer had a significantly reduced tumour burden compared mice did not undergo or those treated saline solution. Peritoneal secretions contaminate reduce its cell-lytic effect. Nonetheless, complete achieved, vivo, by prolonging time exposure contaminated solution 20 min. Conclusion Single is probably safe may have positive influence outcomes. Further evidence required regard sequential lavages as beneficial humans.